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Drugs that are associated with: Medical treatment to help ensure continued sobriety includes self-administration of drugs such as Antabuse Antabuse , trade name for the drug tetraethylthiuram disulfide, used in the treatment of alcoholism. Also called sulfiram, Antabuse is nontoxic, but it alters the metabolism of alcohol in the body, making it impossible for one who is taking the drug to drink without experiencing . Click the link for more information. which produces severe discomfort if present in the system when alcohol is consumed. Naltrexone, a drug formerly used in heroin abuse, and acamprosate are also now approved for use in the treatment of alcoholism. Naltrexone minimizes both the craving for alcohol and the "high" produced by its consumption. Acamprosate reduces the craving for alcohol in people who have stopped drinking. In addition to these standard treatments, many alcoholics are aided by alternative treatments such as acupuncture acupuncture , technique of traditional Chinese medicine, in which a number of very fine metal needles are inserted into the skin at specially designated points. For thousands of years acupuncture has been used, along with herbal medicine, for pain relief and treatment of various . Click the link for more information. and hypnosis. Afhankelijk van het klinische beeld is opname niet altijd nodig, mits voldoende toezicht aanwezig is om contact op te nemen bij verslechtering van het klinische beeld. Een protocol, opgesteld door de kinderartsen, beschrijft de procedure voor jongeren met een alcoholintoxicatie op de spoedeisende hulp en de verdere nazorg [Projectgroep Voorkom alcoholschade bij jongeren 2013]. Het protocol vermeldt de opnamecriteria voor een alcoholintoxicatie: National audits to investigate this phenomenon (NAP5: Accidental Awareness during General Anaesthesia) have been underway in the UK for a number of years. 21 22 The results indicate that the incidence is much less than previously thought, though it is not non-existent. 23 Geographical differences may exist with possibly lower incidences of this complication in Europe than the USA. 24 Such differences may depend on what is being reported and the type of surgery involved. Various professional bodies have sought to inform the general public of the potential risks and to reassure them that a great deal of effort goes into preventing this phenomenon. 25 [0049] If, however, two rings in a multiple ring system each have different substituents drawn from the center of each ring, then, unless otherwise specified, each substituent only represents substitution on the ring to which it is attached. For example, in Formula D6, Y is an optional substituent for ring A only, and X is an optional substituent for ring B only.