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An uncompetitive inhibitor binds only to the enzyme-substrate complex preventing the formation or release of the enzymatic products. Unlike with classical-competitive inhibition an uncompetitive inhibitor need not resemble the structure of the enzymes natural substrate. An uncompetitive inhibitor is most effective at high substrate concentration as there will be more enzyme-substrate complex for it to bind. Unlike with competitive inhibitors the effects of an uncompetitive inhibitor cannot be overcome by increasing the concentration of substrate. What if client is resistant to Suboxone? Use self-help devices such as tools with enlarged handles jar openers or "reachers"--long-handled devices that help you reach high places. These reduce stress on your joints and can make difficult tasks easier. Sheeren, M. (1988). The relationship between relapse and involvement in Alcoholics Anonymous. Journal of Studies on Alcohol, 49 . 104-106. Jenny K. Schuster
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发表于 2016-5-22 15:48:54
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